Moss protein corrects genetic defects of other plants
Plants differ from animals in that they are capable of photosynthesis. They do this in specialized "mini-organs" (biologists speak of organelles), the chloroplasts. Chloroplasts produce sugar with the help of sunlight, which in turn is used in other organelles, the mitochondria, to produce energy.
Both chloroplasts and mitochondria have their own genetic material. And in both of them this genome contains a lot of errors. "At least that is the case with almost all land plants," explains Dr. Mareike Schallenberg-Rüdinger. The researcher heads a junior resear... Read More
Much of longevity and aging research focuses on studying extremely long-lived species, including 
Biomarkers, Cytokines, and Chemokine’s
Understanding the microenvironment within skin cancers is key for the development of new preventative and therapeutic treatment options. Research advances in skin cancers such as melanoma have revolutionized immunotherapeutic treatment options, for example through the provision of checkpoint inhibitor trials that have benefitted not just melanoma patients, but also patients with a wide array of other cancers, including less readily accessible cancer types. However, checkpoint inhibitor success is limited in melanoma and... 
Skin Inflammatory Disorders T cell
The skin is comprised of structural, innate and adaptive immune cells. Defects in any of the three arms disrupts skin homeostasis leading to impaired host defence responses and/or skin inflammatory disorders. Skin inflammatory disorders are a group of heterogenous diseases comprised of immunodeficiencies and autoimmune disorders (Psoriasis, Vitiligo, Alopecia areata, Scleroderma) and immune hyperreactivity (atopic dermatitis, allergic contact dermatitis, prurigo nodularis). For many of these diseases, it is well accepted that dys... 
Psychopathology Research
Psychopathology needs to be viewed as a set of theoretical constructs which can be altered over time and they thus require periodic calibration. Furthermore, the way in which we describe the mental symptoms must be adapted to the scientific needs of the age in which we live related, for instance, with the detail of the data obtained by the auxiliary means of diagnosis and which are different from those observed in the 19th century.
Jaspers had already said with regard to the evolution of psychopathology: «general psych... 
A profound and unexpected disparity in 
It’s not yet clear why some people infected with 
Fungal Pathogens
Surface components in fungal cells include cell wall molecules and, in certain cases, capsular structures. In pathogens, these components are responsible for key events during interaction with the host. These events include recognition of pathogens by the immune system and generation of damage to host cells and tissues. The molecular nature of surface structures in fungi is vast and may include (glyco)proteins, polysaccharides, lipids and pigments. Many of them have been strictly associated with the antifungal immune response, as well as with step... 
Trichoderma species Cellulases Produced by Solid State Fermentation
The main aim of this study was to analyze eight species of Trichoderma for cellulase enzyme production by solid state fermentation. Different carbon sources such as wheat bran, corn cob, sucrose, maltose and filter paper were used. Highest celluase enzyme production was achieved with T. harzianum on media supplemented with corn cob. The optimum pH, temperature and thermal stability of isolated enzymes were also analyzed. The best pH for enzyme production was found between 4-6. The... 
The coding region of a gene, also known as the CDS (from coding sequence), is the portion of a gene's 
The 
Quick Reliable Exploration of the PDB Universe Seeks a New Template
Near-native protein structure prediction through Template Based Modelling (TBM) has been a major realistic goal of structural biology for several years. The TBM algorithms require the best-set of templates for a target protein sequence to maximally cover it and construct its correct topology. However, the accuracy of such prediction algorithms suffers from the algorithmic and logical problems of our template search measures which fail to quickly screen reliable structures for a target sequence. In... 
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.
Several transcriptomics technologies can be used to generate the necessary data to analyse. DNA microarrays measure the relative ac... 
TranscriptLongdom Publishing is a total set of transcripts in a given organism and referred to as an expression profiling that examines the expression level of mRNAs in a given cell population. TranscriptLongdom Publishing includes high-throughput techniques based on 
Visualization of High Throughput Genomic Data Using R and Bioconductor
Neurological Disorders | Pathology
Tauopathies are characterized by the aberrant modification, splicing, and aggregation of the microtubule-associated protein Tau into filamentous inclusions in neurons and glia. Tau pathology is present across a wide spectrum of neurodegenerative diseases including Alzheimer's disease, fronto-temporal dementias, Pick's disease, progressive supranuclear palsy, chronic traumatic encephalopathy, Huntington's and Parkinson's diseases, among others. Given the combined prevalence of these diseases and the importance of T... 
Chronic Kidney Disease
The prevalence of both chronic kidney disease (CKD) and metabolic bone diseases increases with age. Given the aging of the population as a prevailing demographic trend in the Western world, these medical conditions represent a significant challenge.
Moreover, CKD in its advanced stages (from CKD grade 3) is associated with changes of calcium-phosphate metabolism, which, together with the lack of active di-hydroxylated vitamin D, constitute mineral and bone disease that is connected with CKD (CKD-MBD). The bone component of CKD-MBD (re... 
Brain Pathology
The Transient Receptor Potential (TRP) channels compromise a superfamily of polymodal receptors that are critically involved in the detection of diverse stimuli such as temperature or pH changes, noxious chemicals or mechanical forces. This ability to sense environmental changes is essential for survival, and thus the disruption of TRP channel function can have a severe impact on human health, as evidenced by the increasing number of hereditary and acquired diseases linked to TRP channels. Many members of the TRP channel superfamily are expressed i... 
Current Synthetic and Systems Biology is an open access journal publishing original peer-reviewed research articles in experimental and theoretical aspects of the function of biological systems at the molecular, cellular or organismal level, in particular those addressing the engineering of biological systems, network modelling, quantitative analyses, integration of different levels of information and synthetic biology
Current Synthetic and Systems Biology is a peer reviewed scientific journal known for rapid dissemination of high-quality research. This Current Synt... 
Current Synthetic and Systems Biology research objective is to encourage and assist the development of better and faster measures of systems-biology. In cases where we believe we can contribute directly, as opposed to through highlighting the work of others, we are producing our own measures of research activity. Our work is mainly of interest to investors, organizations and individuals in the financial sector and to significant corporations with global operations, as well as governments and academic researchers.
Current Synthetic and Systems Biology play a key role in the knowled... 
Conservation strategies in natural habitats as well as in breeding centers are necessary for maintaining and reinforcing viable populations of wild felids. Among the fundamental knowledge that is required for conservation breeding, a solid understanding of reproductive 
Gene Synthesis
Current Synthetic and Systems Biology is aimed at everyone working in the modelling and discovery of emergent properties in complex biological systems. Also, it seeks scientists relating the structure and dynamics of living organisms with their physiology and phenotypic traits for the understanding of the whole. In addition to the highest-quality original articl... 
SYNTHETIC BIOLOGY
Current Synthetic and Systems Biology is an journal that provides an opportunity to researchers and scientist to explore the advanced and latest research developments in the field of synthetic and system biology and related academic disciplines.
The Editors select manuscripts based on their novelty and wide biological significance. Although the primary emphasis of the journal is ... 
The scientists discovered close to 200,000 DNA markers in Asians, which had been previously unreported in existing genetic databases. The catalogues that are now used for disease-association studies in Asia, including India, are those that have primarily been generated in western populations, hence of limited use in Asia.” The scientists also found 23 per cent of previously unreported protein variants. “Since alterations of proteins are usually associated with disease, we specifically investigated those ... 
The mammalian circadian clock includes a “master clock” within the suprachiasmatic nucleus (SCN) of hypothalamus and “peripheral clocks” within other tissues of the body. The “master clock” functions as an “orchestra conductor” to direct “peripheral clocks” through yet-to-be defined pathways, allowing animals to adapt their feeding, activity, and metabolism to predictable daily changes in the environment.
Circadian clocks orchestrate physiological rhythms via the temporal regulation of gene expression to control core cloc... 
Combining biological research and engineering
On behalf of the Journal, as Editor-in-Chief, it is my distinct honor and privilege to welcome you to the Current Synthetic and Systems Biology
The journal aims to spread knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to Modern Scientific Techniques. The open access journal is published by L... 
Current Synthetic and Systems Biology
The Current Synthetic and Systems Biology aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to like molecular biology, theoretical biology, structural biology, marine biology etc..
The Journal emphasizes high-level research and education. Original research articles, revi... 
Major Considerations and Outcomes of Clinical Studies on Vitamin D Deficiency in Patients with Crohn's
Introduction: The literature shows a bimodal incidence of Crohn's disease in relation to age, with peaks from 15-40 and from 50-80 years and more women have Crohn's disease than men. Clinical studies have shown a direct correlation of vitamin D deficiency with Crohn's disease.
Objective: Using a systematic review, the objective of this study was to identify the main correlations and outcomes of clin... 
Bioinformatics
Bioinformatics can be defined as “the application of computational tools to organize, analyze, understand, visualize and store information associated with biological macromolecules”.
Bioinformatics is an interdisciplinary scientific field of life sciences. Bioinformatics research and application include the analysis of molecular sequence and genomics data; genome annotation, gene/protein prediction, and expression profiling; molecular folding, modeling, and design; building biological networks; development of d... 
On behalf of the Journal, as Editor-in-Chief, it is my distinct honour and privilege to welcome you to the Journal of Theoretical and Computational Science.
The 
Clinical-Therapeutic Importance of Bioimpedance in Patients with Lymphedema
Introduction: Lymphedema is characterized by abnormal accumulation of macromolecules and soft tissue fluids. Bioimpedance is a method that measures intra- and extracellular volumes by body segment, and has been currently used in lymphedema.
Objective: The objective of this study was to conduct a systematic review of the clinical-therapeutic importance of bioimpedance in patients with lymphedema.
Methodology: The present... 
Tumor Genomics
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On behalf of the Journal, as Editor-in-Chief, it is my distinct honour and privilege to welcome you to the Journal of Theoretical and Computational Science.
The 
The team “
Most Cited editorial was published in Transcriptomics: Open Access Journal was by editor Alireza Heidari in 2017 entitled “
On behalf of the 
On behalf of the Journal, as Editor-in-Chief, it is my great pleasure and honour to welcome you to the Journal of Theoretical and Computational Science.
The 
Mathematica Eterna is established in the year of 2011 publishes updated scholarly information on Mathematics from wide range of geographies across the world. During this year we look forward to taking some initiates that would encourage and reward our prospective customers....