Guillain-Barre syndrome (GBS) is an acute demyelinating inflammatory mediated polyneuropathy mediated by the immune system that leads to generalized flaccid paralysis. Most GBS cases are preceded by viral or bacterial infections of the respiratory or gastrointestinal tract, developing an aberrant response that causes autoantibody formation and complement and cytokine activation. Because it is a rare disease, diagnosis is often slow and may worsen the clinical picture. The patient should be evaluated by a multidisciplinary team and the treatment of choice is intravenous human immunoglobulin. We report a case in which the patient had several symptoms resulting from GBS, probably developed by the previous infection, but only had the disease diagnosed late, leading to a worsening of her clinical condition and compromising her quality of life. Since 1976, several studies have established a causal relationship between GBS and vaccines, especially Influenza A, but the pathophysiological mechanism remains unknown. However, it is known that there is a greater chance of GBS development due to Influenza a virus infection than vaccination. Studies reveal that there are environmental and genetic components that may influence susceptibility to disease. However, there is little research on the polymorphism of immune response genes and their influence on the development of the syndrome. Some cases of involvement of people belonging to the same family have been reported in the literature, thus demonstrating that the presence of genetic components influencing the predisposition to GBS cannot be ruled out.
To know more about the journal kindly visit at: https://www.longdom.org/open-access/guillainbarre-syndrome-case-study-and-literature-review.pdf
How we work:
- After submission, an acknowledgement with manuscript number is sent to the corresponding author within 7 working days.
- A 21 day window time frame is allotted for peer-review process wherein multiple experts are contacted.
- Author proof is generated within 7 working days after the acceptance decision.
Benefits on Publication:
Open Access: Permanent free access to your article upon publication ensures extensive global reach and readership.
Easy Article Sharing: Our open access enables you to share your article directly with colleagues through email and on social media via a single link, permitting third party reuse with appropriate citation in addition to the retention of content copyright by the author.
Global Marketing: Through promotion in a targeted global email announcement or press release, your article will be seen by thousands of the top-most thought-leaders in your field.
Color Art: In a world of black & white journal articles, high-quality full-color images make your article stand out from the crowd and tell a complete story, increasing readers and citations.
Social Media Exposure: Extended reach for your article through links on Twitter accounts provides maximum visibility worldwide.
Reprints: Distribute your work to colleagues and at conferences as we provide hard copy color reprints of your article on order.