Cardiopulmonary Exercise Testing


Cardiopulmonary Exercise Testing

CPET may be performed at rest or under conditions of varying (e.g. ramped) or fixed ranged of external workloads to assess physiological stress responses. Heart rate, oxygen saturations, blood pressure and electrocardiogram can all be measured simultaneously along with inspired/expired gas analysis. In this way, CPET may provide a global assessment of the integrated response of the respiratory, cardiac, metabolic and haematological systems that are not adequately measured when only one organ is assessed at a time at rest.

Cardiopulmonary Exercise Testing (CPET) is a non-invasive assessment to quantify the combination of the heart as a pump and the lungs working as a set of respiratory apparatus to measure aerobic capacity. CPET may provide an objective method to evaluate functional physical capacity for exercise. CPET integrates expired oxygen and carbon dioxide gas concentration along with ventilatory flow to derive oxygen uptake (defined as VO2 and at peak work output,VO2max) and carbon dioxide production (defined as VCO2) has allowed for recommendations for CPET use in clinical practice. Commonly, there are two modes of exercise assessment; cycle ergometer or running treadmill. Cycle ergometer makes a better assessment of external workload, requires less space and participant performance is less affected by practice or biomechanics.

Cardiopulmonary exercise testing (CPET) is a reliable, reproducible and non-invasive measure of functional capacity. CPET has been increasingly used to assess pre-operative risk and stratify patients at risk of mortality and morbidity following surgery. CPET parameters that predict outcomes within liver and pancreas cancer surgery still remain to be defined.


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