Risk Factors for Febrile Seizures in Children

Objective: we aimed to identify the factors associated with febrile seizures (FS) occurrence.

Methods: This was a case-control study. Sixty cases of FS were prospectively recorded and compared to 60 controls admitted for fever without seizures.   Baseline Data were collected from all consecutive patients and laboratory hematological parameters including complete blood count, serum iron, serum ferritin and zinc levels were performed prospectively the first day of admission.  The two groups were compared to identify parameters associated with FS occurrence. All statistical analysis was performed with SPSS software, version 19.

Results: The mean age was 18 ± 12.7 months in cases and 20 ± 13.9 months in controls. The consanguinity rate was significantly higher in cases than in controls (p=0.028). A positive family history of febrile seizures was found in 22 cases (36.7%) which was statistically significant as compared to controls (p=0.003). In contrast, there was no significant statistical difference noted when considering the positive family history of epilepsy (p=0.43). Gestational age, weight birth and breastfeeding duration were significantly lower in cases (p=0.002, 0.023 and <0.0001 respectively). Similarly the duration of fever was lower in cases group (10.7 ± 17.4 vs 35.6 ± 18.4 hours, p<0.001). Mean hemoglobin, serum iron, ferritin and zinc were significantly lower in cases than controls. Multivariate analysis identified four factors associated with FS occurrence:  family history of FS, duration of breast-feeding less than 6 months, rapid rise of body temperature and iron deficiency anemia.

Conclusion:  in children with personal or family history of FS. Clinicians should particularly incite breastfeeding and prevent micronutrient deficiencies, especially iron deficiency.

A standard editorial manager system is utilized for manuscript submission, review, editorial processing and tracking which can be securely accessed by the authors, reviewers and editors for monitoring and tracking the article processing. Manuscripts can be uploaded online at Editorial Tracking System (https://www.longdom.org/submissions/medical-surgical-pathology.html) or forwarded to the Editorial Office at: surgpathology@emedsci.com

To know more about the article: https://www.longdom.org/medical-surgical-pathology.html

How we work:

After submission, an acknowledgement with manuscript number is sent to the corresponding author within 7 working days.

A 21 day window time frame is allotted for peer-review process wherein multiple experts are contacted.

Author proof is generated within 7 working days after the acceptance decision.

Benefits on Publication:

Open Access: Permanent free access to your article upon publication ensures extensive global reach and readership.

Easy Article Sharing: Our open access enables you to share your article directly with colleagues through email and on social media via a single link, permitting third party reuse with appropriate citation in addition to the retention of content copyright by the author.

Global Marketing: Through promotion in a targeted global email announcement or press release, your article will be seen by thousands of the top-most thought-leaders in your field.

Color Art: In a world of black & white journal articles, high-quality full-color images make your article stand out from the crowd and tell a complete story, increasing readers and citations.

Social Media Exposure: Extended reach for your article through links on Twitter accounts provides maximum visibility worldwide.

Reprints: Distribute your work to colleagues and at conferences as we provide hard copy color reprints of your article on order.

Media Contact:
Marcy A
Journal Manager
Journal of Medical and surgical pathology
Email: surgpathology@emedsci.com